CAS 122666-87-9 L-Tyrosine Disodium Salt Dihydrate Cell Culture Media 69847-45-6

CAS 122666-87-9 L-Tyrosine Disodium Salt Dihydrate Cell Culture Media 69847-45-6

Description

L-Tyrosine disodium salt dihydrate is a sodium salt of the essential amino acid L-Tyrosine. The "dihydrate" indicates that two water molecules are associated with each molecule of the salt. This modification significantly enhances the solubility of L-Tyrosine in aqueous solutions compared to its free acid form.

Its chemical formula is C₉H₉NNa₂O₃·2H₂O, and its CAS Number is 69808-84-0. It appears as a white to off-white crystalline powder. In biochemical and cell culture applications, it serves as a readily available source of L-Tyrosine, a crucial precursor for the synthesis of neurotransmitters (like dopamine, epinephrine, and norepinephrine), thyroid hormones, and melanin.

Specification Table

Key Features

1. High Solubility: The disodium salt form is highly soluble in water, making it ideal for preparing concentrated stock solutions for cell culture media and biochemical buffers, unlike the poorly soluble free acid form.
2. Biologically Active: It is the pure L-enantiomer, which is the natural and biologically active form utilized by mammalian cells.
3. Essential Precursor: Provides a direct source of tyrosine for the biosynthesis of critical biomolecules like catecholamines and thyroid hormones.
4. Defined Composition: High purity and consistent quality ensure reliable and reproducible results in research and manufacturing processes.
5. Cell Culture Grade: When certified, it is suitable for use in cell culture applications, fulfilling the stringent requirements for sterility and endotoxin levels.

Applications

• Cell Culture Media: A key component in defined serum-free media and classic media formulations (e.g., DMEM, RPMI-1640) as a source of tyrosine for protein synthesis and cellular metabolism.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway research, particularly those involving the tyrosine hydroxylase enzyme and the synthesis of neurotransmitters.
• Pharmaceuticals: Can serve as a raw material in the synthesis of pharmaceutical compounds, including certain drugs and diagnostic agents.
• Microbiology: Used in microbiological culture media to support the growth of fastidious microorganisms that require specific amino acids.
• Animal Nutrition: Although less common than the free acid form, it can be used in specialized animal feed and veterinary nutrition studies.

Storage & Handling

• Storage Conditions: Store in a cool, dry, and well-ventilated place. The container must be kept tightly closed to prevent absorption of moisture from the atmosphere (it is hygroscopic) and exposure to light.
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• Handling: Handle with appropriate personal protective equipment (PPE), including a lab coat, gloves, and safety glasses. Avoid creating airborne dust. Use in a well-ventilated area.
• Stability: The compound is stable under normal laboratory conditions but is incompatible with strong oxidizing agents.